SAMe (S-Adenosyl-Methionine)

USD $52.50
400 mg, 60 enteric-coated vegetarian tablet
Item #
02174
Mood, joint & liver support
  • 4 Units @ USD $48.00 | Save USD $4.50

Our Best Seller SAMe, or S-Adenosyl-Methionine, benefits many critical metabolic functions in the body. This amazing compound helps maintain a stable mood and supports both joint and liver health.

Non-GMO | Vegetarian

Overview

What Is SAMe?

SAMe participates in many critical metabolic functions by donating methyl groups to other molecules. Methyl groups need to be transferred between compounds in the body to help with things like neurotransmitter signaling and protein function. Laboratory research has shown that SAMe levels appear to decline over time.

SAMe is a compound that has been studied by numerous scientists, researchers and even the U.S. government.

SAMe Benefits

  • Helps maintain stable mood
  • Promotes liver health
  • Supports healthy joint function
 
 

SAMe

SAMe: Subject of Government Research

There is so much research on SAMe that the U.S. Department of Health and Human Services conducted a meticulous evaluation of the evidence. The analysis showed that SAMe has helped maintain stable mood and joint function in several studies.

Product details

S-adenosyl-methionine (SAMe), is made naturally by your body. It participates in many critical metabolic functions by donating methyl groups to other molecules. Methyl groups need to be transferred between compounds in the body to help with things like neurotransmitter signaling and protein function.1,2

Mood, joint & liver health

SAMe helps maintain stable mood3 and joint comfort.4 It also supports liver health, which is not surprising since a large portion of the body's SAMe is made in the liver.5 But SAMe levels decline over time.6

SAMe supports your body's antioxidant defenses by donating sulfur molecules to help with the production of glutathione, one of the body's most important natural antioxidants.7

There is so much research on SAMe that the U.S. Department of Health and Human Services conducted a meticulous evaluation of the evidence. The analysis showed that SAMe has helped maintain stable mood and joint function in several studies.8

Supplementing with SAMe is one way to support the numerous bodily functions that depend on the fascinating biochemical properties of this vital molecule.

 

References

 

  1. Biochim Biophys Acta Bioenerg2016 2;1857(8):1073-1078.
  2. J Am Coll Nutr. 2001;20(6):591-598.
  3. Mitochondrion. 2007;7:S2-S7.
  4. Curr Atheroscler Rep. 2018;20(6):29.
  5. Clin Physiol. 1988;8(4):391-398.
  6. Neuropsychiatric Disease and Treatment. 2009;5:597-610.
  7. Mitochondrion. 2007;7:S41-S50.
  8. Mol Biotechnol. 2007;37(1):31-37.
  9. Front Physiol. 2018;9:44.
  10. Mech Ageing Dev. 2010;131(4):225-235.
  11. Recent Pat Drug Deliv Formul. 2010;4(3):245-255.
  12. Exp Neurol. 2004;188(2):491-494.
  13. Kaneka Corp. CoQ10 reducing activity in rats. Unpublished internal study data.
  14. Regul Toxicol Pharmacol. 2006;47(1):19-28.
  15. Nutraceuticals. Boston: Academic Press; 2016:707-716
  16. Phytotherapy Research. 2014;28(4):475-479.
  17. J Ethnopharmacol. 2011;136(1):1-9.
  18. Systemic CoQ level in animals: Part II. Unpublished study. Natreon, Inc.; 2007.
  19. Shilajit in Perspective. Alpha Science International Limited; 2006.
  20. Sustained Energy for Enhanced Human Functions and Activity. Academic Press; 2017:187-204
  21. Biochemistry. 2017;56(50):6615-6625.
  22. J Nutr Biochem. 2013;24(12):2076-2084.
  23. Biochem Biophys Res Commun. 2007;363(2):257-262.
  24. Exp Gerontol. 2006;41(2):130-140.
  25. Pharmacologyonline. 2009;1:817-825.
Supplement Facts

Serving Size 1 enteric coated vegetarian tablet

Amount Per Serving

S-Adenosyl-Methionine

400 mg

Other ingredients: cellulose, methacrylic acid copolymer, mannitol, citric acid, titanium dioxide, stearic acid, silica, hydroxypropyl methylcellulose, glyceryl triacetate, sodium starch glycolate, croscarmellose sodium, yellow ochre.

Non-GMO

Dosage and Use
  • Take one (1) tablet one to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner..
  • Take with co-factors vitamins B12, B6, and folic acid.
Caution
  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
  • SAMe should not be taken by those diagnosed with bipolar disorder.

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