PQQ

Your mitochondria supply energy to the cells throughout your body. But as you age, your number of functional mitochondria declines.^1,2 PQQ (pyrroloquinoline quinone) can activate genes that promote the growth of brand-new mitochondria, which promotes cellular energy for your entire body. ^3,4

Mitochondria are as fascinating as they are essential: They have their own set of DNA. Even the growth of new mitochondria has a name: “mitochondrial biogenesis.” Mitochondrial biogenesis is key to maintaining youthful cellular energy production. PQQ also supports mitochondrial biogenesis and encourages healthy cellular energy levels in 3 distinct ways:

Mitochondrial DNA & antioxidant protection

The enormous amount of cellular energy generated within mitochondria also exposes them to constant free radical activity. Fortunately, PQQ is a potent antioxidant, offering powerful free radical protection and maximum support for cellular energy production at the same time.⁵

Mitochondria possess their own DNA, which is different from the DNA found in a cell’s nucleus. Unfortunately, mitochondrial DNA is more vulnerable to mutations than nuclear DNA. PQQs antioxidant potency and favorable gene expression profile help to support delicate mitochondrial DNA against oxidation.

Favorable gene expression

PQQ activates genes that promote the formation of new mitochondria.¹⁰ PQQ also beneficially interacts with genes directly involved in mitochondrial health. These same genes also support healthy sugar and fat metabolism, youthful cellular proliferation and more.^6,7,11

Other potential whole-body health benefits

PQQ may support quality, restful sleep, heart health and cognitive function, by itself and in combination with CoQ10.^8-13 Plus, when taken with CoQ10, PQQ promotes memory, attention and cognition in maturing individuals.

Reference

1. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 1995;1271(1):165-170.
2. Diabetologia. 2008;51(8):1440-1443.
3. J Biol Chem. 2010;285(1):142-52.
4. Biochemistry. 2017;56(50):6615-6625.
5. The Journal of nutritional biochemistry. 2013;24(12):2076-2084.
6. Journal of Biological Chemistry. 2009:jbc. M109. 030130.
7. PloS one. 2011;6(7):e21779.
8. Functional foods in health and disease. 2012;2(8):307-324.
9. Biochem Biophys Res Commun. 2007;363(2):257-62.
10. Adv Exp Med Biol. 2016;876:319-25.
11. Adv Exp Med Biol. 2016;923:215-22.
12. Heliyon. 2017;3(4):e00279.
13. J Clin Biochem Nutr. 2008;42:29-34.