Specially-Coated Bromelain

Bromelain, a mixture of proteases extracted from the stem of the pineapple, has been used by Europeans for many years to inhibit inflammatory factors to support joint health.

How bromelain works

Bromelain’s fluid-regulating properties may result from its ability to inhibit inflammatory cytokine production to support joint health, inhibit neutrophil migration and more. Preclinical research also shows that bromelain may help support healthy blood viscosity and blood platelet aggregation.^1-3

Enteric coated to bypass stomach

Bromelain has to be enteric coated so that it will not be activated in the stomach and used as a digestive enzyme. Enteric-coated bromelain tablets pass into the small intestine, where the bromelain is absorbed into the bloodstream to provide systemic benefits.⁴

Clinically studied to support joint health

Specially-coated bromelain promotes a healthy inflammatory response to support joint health. Research has demonstrated that enteric-coated bromelain formulations are at least as effective as other approaches in supporting joint comfort, function and health.⁵

One clinical study found that bromelain is more effective than other methods for maintaining joint function at rest (41 percent for bromelain vs. 23 percent for other methods).⁶ Another clinical study showed that specially-coated bromelain yielded an overall improvement in general well-being, along with improvement in comfort and physical function.⁷

References

1. Int Immunopharmacol. 2004;4(2):255-264.
2. Biomed Rep. 2016;5(3):283-288.
3. Mutat Res. 2004;555(1-2):53-64.
4. Jpn Heart J. 1971;12(6):517-527.
5. Curr Pharm Biotechnol. 2018;19(11):886-895.
6. Clin Rheumatol. 2004;23(5):410-415.
7. Clin Exp Rheumatol. 2006;24(1):25-30.