Acetyl-L-Carnitine

Acetyl-L-carnitine facilitates the movement of fatty acids into mitochondria, where they can be burned as fuel to produce energy. Thus, acetyl-L-carnitine helps to support whole-body energy production.

Acetyl-L-carnitine supplementation has been shown to benefit energy-intensive body systems such as the nervous system and the cardiovascular system, and to help counteract the age-related increase in oxidative stress and the decrease in mitochondrial efficiency that occurs with advancing years.^1-5

Acetyl-l-carnitine has wide-ranging benefits for nervous system wellness, including the central and peripheral nervous systems, and cognitive health, as well as positive mood.^6-11 It has been shown to promote peripheral nervous system comfort, support healthy mood, energy and overall well-being.^12-17

Reference

1. LPI. L-carnitine. Accessed 06/01/2019. https://lpi.oregonstate.edu/mic/dietary-factors/L-carnitine
2. Front Biosci (Landmark Ed). 2016;21:1314-29.
3. Adv Drug Deliv Rev. 2009;61(14):1332-1342.
4. Ann N Y Acad Sci. 2004;1033:108-16.
5. J Clin Hypertens (Greenwich). 2007;9(4):249-55.
6. Expert Review of Neurotherapeutics. 2013;13(8):925-936.
7. Zh Nevrol Psikhiatr Im S S Korsakova. 2011;111(9):16-22.
8. Metab Brain Dis. 2011;26(4):281-9.
9. Amyotroph Lateral Scler Frontotemporal Degener. 2013;14(5-6):397-405.
10. Eur Neuropsychopharmacol. 2013;23(10):1219-25.
11. Proceedings of the National Academy of Sciences of the United States of America. 2018;115(34):8627-8632.
12. Clin Exp Rheumatol. 2015;33(1 Suppl 88):S82-5.
13. Scandinavian Journal of Gastroenterology. 2011;46(6):750-759.
14. J Interferon Cytokine Res. 2011;31(9):653-9.
15. Am J Clin Nutr. 2011;93(4):799-808.
16. J Diabetes Investig. 2016;7(5):777-85.
17. Oncologist. 2013;18(11):1190-1.